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Message: A colleague has chosen to send you a link to the SQUIRE website. Please find a summary and the link below. Considers possible sources of confounding, bias, or imprecision in design, measurement, and analysis that might have affected study outcomes (internal validity) Explores factors that could affect generalizability (external validity), for example: representativeness of participants; effectiveness of implementation; dose-response effects; features of local care setting Addresses likelihood that observed gains may weaken over time, and describes plans, if any, for monitoring and maintaining improvement; explicitly states if such planning was not done Reviews efforts made to minimize and adjust for study limitations Assesses the effect of study limitations on interpretation and application of results http://squire-statement.org/28/